Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth

This observational study, called "Healthy Start," is looking into how a mother's diet during pregnancy might affect her child's health later in life. Researchers want to see if too much nutrition for the baby while in the womb (fetal over-nutrition) is linked to obesity, problems with metabolism (how the body uses food for energy), and heart issues in children. They are studying pregnant women and their babies. To join, you must be a pregnant woman living in Colorado, less than 23 weeks pregnant, and not have certain health conditions like multiple pregnancies, cancer, or diabetes. The study will measure the baby's fat mass at birth and again at 5 years old to see if there's a connection.

Study design
This is an observational study planning to enroll 2821 participants. It follows a group of ethnically diverse pregnant women and their children over time.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' children will have their fat mass measured at birth and again at 5 years of age.

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NCT02273297

Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth

UNKNOWN
Not specifiedAges 16+Observational
University of Colorado, Denver
~2,821 participants
Updated 2024-03-15 on ClinicalTrials.gov
What's tested:Maternal factors

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Fat mass
Measured over Birth
+1 more outcome measured
Pregnancy
Obesity
1 sites across 1 states
Colorado1
  • Dana Dabelea, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

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Eligibility criteria

Inclusion

Pregnant women and infants
Prior to 23 completed weeks of gestation
Live in Colorado

Exclusion

Multiple gestation
Preexisting
cancer
psychiatric disease
steroid-dependent asthma, or
diabetes
Previous premature delivery prior to 25 weeks gestation or fetal demise
  • Fat massBirth

    Body composition assessed via air displacement plethysmography to calculate fat mass and fat-free mass.

  • Fat mass5 years

    Body composition assessed via air displacement plethysmography to calculate fat mass and fat-free mass.