Real-World Registry of Chronic Wounds and Ulcers

This is an observational study, called WOUNDJOURNEY, that collects information about people with chronic wounds or ulcers, such as diabetic foot ulcers, pressure ulcers, or surgical wounds. It's not testing a new treatment, but rather observing how different types of chronic wounds are treated in real-world settings across the USA and Puerto Rico. The study aims to understand the full journey of patients with these wounds. Researchers will look at whether wounds heal, and if major or minor amputations are needed, all measured at one year. You could be included if you have one or more chronic wounds or ulcers of any type, and your care is documented at a participating clinic using a special electronic health record system. The study is ongoing and has been collecting data since 2005.

Study design
This is an observational registry study, not testing a specific intervention, and plans to include 300,000 participants. It collects data during routine care from over 1,400 clinicians.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcomes, such as healing and amputations, are measured at one year.

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NCT02280733

A Real-World Registry of Chronic Wounds and Ulcers

Recruiting
Not specifiedAll AgesObservational
U.S. Wound Registry
~300,000 participants
Updated 2025-07-16 on ClinicalTrials.gov
What's tested:Usual care

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Healed
Measured over 1 year
+3 more outcomes measured
Diabetic Foot
Pressure Ulcer
Surgical Wound Dehiscence
Vasculitis
Skin Ulcer
Leg Ulcer
Pyoderma
Peripheral Arterial Disease
Lymphedema
Surgical Complication
Venous Leg Ulcers (VLUs)
Calciphylaxis
Sickle Cell Ulcer
Pressure Ulcer (PU)
Diabetic Foot Ulcers (DFUs)
Pressure Injury
Arterial Ulcers
Soft Tissue Radionecrosis (STRN)
Traumatic Wounds
Chronic Ulcer
1 sites across 1 states
Texas1
  • Caroline E Fife, MD · PRINCIPAL_INVESTIGATOR · Intellicure LLC

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Eligibility criteria

Inclusion

Presence of one or more chronic wounds or ulcers of any etiology
Wound or ulcer must be treated at a participating site (which can be a hospital outpatient department, office, mobile practitioner, in the home setting, skilled nursing, etc.)
Care must be documented using the purpose-built, wound-specific structured electronic health record (EHR) or electronic data capture (EDC) system
All ages, including infants and patients aged 90 years or older (reported in aggregate in accordance with HIPAA de-identification standards)
All sexes and gender identities
All wound types and severities, including multiple wounds per patient
  • Healed1 year

    Wound closure by secondary intention

  • Major amputation1 year

    Below the knee, above the knee

  • Minor amputation1 year

    toe amputation, transmetatarsal amputation, midfoot amputation

  • Patient Death1 year

    patient death while in treatment