Cardiovascular Health Improvement Project

This project aims to create a collection of clinical information, DNA, plasma (the liquid part of blood), and aortic tissue samples from people with cardiovascular diseases like aortic aneurysm (a bulge in the aorta) or heart failure, as well as healthy volunteers. The goal is to build a comprehensive database and biobank (a storage facility for biological samples) that researchers can use to study these conditions. You might be able to join if you are over 18 and willing to give consent, or if you are under 18 with parental consent. You would also need to have a diagnosis of certain aortic conditions, such as an aortic aneurysm or other interesting vascular issues. The study is currently ongoing, but the exact recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to enroll 15,000 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary goal of establishing a biobank of patients with Aortic Disease is measured at 40 years.

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NCT02306200

Cardiovascular Health Improvement Project

Recruiting
Not specifiedAll AgesObservational
University of Michigan
~15,000 participants
Updated 2026-04-29 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Establishing a biobank of patients with Aortic Disease
Measured over 40 years
Aortic Aneurysm
Aortic Dissection
Bicuspid Aortic Valve (BAV)
Heart Failure
Cardiovascular Diseases
1 sites across 1 states
Michigan1
  • Marion A Hofmann Bowman, PhD, MD · PRINCIPAL_INVESTIGATOR · University of Michigan

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Eligibility criteria

Inclusion

Any patient over the age of 18 who is able/willing to give informed consent
Patients \<18 years of age with parental consent and assent (if assent is applicable for their age)
Diagnosis of:
aortic pathology potentially due to a known or suspected inherited condition
Idiopathic aortic aneurysm
Interesting of novel vascular pathology in the aorta or main branches
Family history of aortic or vascular disease
Other cardiovascular disease
Healthy controls with no apparent cardiovascular disease
  • Establishing a biobank of patients with Aortic Disease40 years

    Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease