Study of Placental Function in Healthy and Pathological Pregnancies

This observational study aims to create a collection of human placentas, umbilical cord blood, and maternal blood samples at the time of delivery. Researchers will use these samples to understand how changes in the placenta (the organ that develops in your uterus during pregnancy) can lead to serious pregnancy problems and affect a baby's health later in life, potentially increasing their risk for metabolic and heart diseases. The study is looking for women aged 18 to 45 who are having healthy pregnancies or those with complications like preterm birth, restricted baby growth, diabetes, or obesity. The main goal is to collect and store these samples for 50 years. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 1250 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Specimens will be stored for 50 years in a repository, but it is not specified if participants will have follow-up after delivery.

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NCT02321007

Study of Placental Function in Healthy and Pathological Pregnancies

Recruiting
Not specifiedAges 18–45Observational
University of Colorado, Denver
~1,250 participants
Updated 2026-02-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Collecting, processing, and archiving human specimens from 1250 subjects
Measured over Specimens will be stored for 50 years in repository
Pregnancy
1 sites across 1 states
Colorado1
  • Thomas Jansson, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

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Eligibility criteria

Inclusion

Healthy women delivering at term
Women with pregnancy complications such as:
pre-term birth,
intrauterine growth restriction,
diabetes, and
obesity.

Exclusion

Women:
under stress,
experiencing pain of labor.
Pregnancies complicated by other pathologies.
  • Collecting, processing, and archiving human specimens from 1250 subjectsSpecimens will be stored for 50 years in repository

    Human placental tissue, umbilical cord blood, and maternal blood samples will be collected from pregnant women at the time of their delivery. The samples will be used to enhance understanding of the role of the placenta in the development of pregnancy complications and in programming of adult disease.