Evaluating Next Generation CT Reconstruction (NextGenIR)

This study is looking at new ways to create CT (Computed Tomography) scans. CT scans make detailed pictures of your body using radiation. Researchers want to see if these newer methods, which use less radiation, produce images that are just as good as images from traditional CT scans. You might be able to join if you are an adult (18 years or older) and are already scheduled for a CT scan of your chest, abdomen, and pelvis with contrast. The study will compare the quality of images from a low-radiation CT scan using advanced reconstruction methods with images from a standard-dose CT scan.

Study design
This is an observational study, meaning researchers will observe and compare CT images from 215 participants. It is not specified if it's randomized or blinded.
What's involved
You would undergo a research low-radiation body CT scan in addition to your clinically indicated CT scan. Image quality will be measured at baseline (Day 0).
Compensation
Not stated in the trial record.
Follow-up
Image quality will be measured at baseline (Day 0).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02417714

Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

Recruiting
Not specifiedAges 18–99Observational
National Heart, Lung, and Blood Institute (NHLBI)
~215 participants
Updated 2026-08-07 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Compare with respect to 6 image quality metrics the overall image quality from a research low radiation dose body CT utilizing advanced (model based) iterative reconstruction with a clinical standard radiation dose CT from the same subject.
Measured over Baseline (Day 0)
Healthy Subjects
1 sites across 1 states
Maryland1
  • Marcus Y Chen, M.D. · PRINCIPAL_INVESTIGATOR · National Heart, Lung, and Blood Institute (NHLBI)

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  • Compare with respect to 6 image quality metrics the overall image quality from a research low radiation dose body CT utilizing advanced (model based) iterative reconstruction with a clinical standard radiation dose CT from the same subject.Baseline (Day 0)