This study is exploring how exercise and diet might affect appetite and the brain's response to food in people with schizophrenia. Researchers are also looking at how common medications like olanzapine, risperidone, clozapine, or haloperidol might contribute to weight gain. You could be eligible if you are 21-70 years old, have schizophrenia or schizoaffective disorder, and are either taking one of these medications or no neuroleptic (antipsychotic) medications. The study will measure how your brain responds to food images and ask about your food preferences and symptoms. The goal is to see if exercise or diet changes these brain responses after 14 weeks.

Study design

This is an interventional study planning to enroll 140 participants. It will evaluate the effects of exercise and diet.

What's involved

You would have your brain's response to visual food cues and resting-state brain activity measured. You may also be asked to complete an exercise or diet intervention.

Compensation

Not stated in the trial record.

Follow-up

Your neuronal responses will be measured at 14 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.