Personalized Cancer Therapy Study

This study aims to understand how personalized cancer treatments work, including how well they treat cancer and what side effects they cause. Researchers will look at your medical records to see if your doctors chose treatments based on the genetic makeup of your tumor, and how you responded. They will also collect information about the tests and treatments you received. Optional research tests may be done on tissue, blood, or urine samples that are already being discarded or collected for this study. The study is looking for 10,000 participants of all ages (7 years and older) and genders. Success will be measured by comparing tumor biomarker profiling (looking at specific substances in your tumor) to how well you respond to treatment, over 4 years. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information from medical records and optional samples. It plans to include 10,000 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your treatment outcome will be measured for 4 years.

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NCT02478931

Study of Personalized Cancer Therapy to Determine Response and Toxicity

Recruiting
Not specifiedAges 7+Observational
Shu Mei Kato
~10,000 participants
Updated 2026-03-31 on ClinicalTrials.gov

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Comparison of Tumor Biomarker Profiling to Treatment Outcome
Measured over 4 years
Cancer
3 sites across 1 states
California3
  • Shumei Kato, MD · PRINCIPAL_INVESTIGATOR · University of California, San Diego

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Must be willing to provide informed consent, parent permission, or assent

Exclusion

Subjects unable to give informed consent, parent permission, or assent
  • Comparison of Tumor Biomarker Profiling to Treatment Outcome4 years

    Tumor molecular profiles will be correlated to treatment outcome, assessed by measures including the response rate, the rate of stable disease (SD)\>6months/partial response (PR)/complete response (CR), progression-free survival (PFS), PFS ratio (comparison of the PFS used after molecular profiling to PFS on prior treatment), time to treatment failure, and overall survival. Logistic regression models (univariable and multivariables) will be used when the outcome variable is dichotomous. Kaplan-meier curves will be used for time-to event outcomes, and comparisons will be done with the log-rank test and Cox regression models.