Back to search results

Biorepository for Undiagnosed and Cardiovascular Diseases

This study is collecting blood and tissue samples to help researchers better understand diseases like undiagnosed conditions and cardiovascular disease. They are looking for people of all ages, from 1 month to 100 years old, who have these conditions, as well as healthy individuals to serve as a comparison. The goal is to identify the underlying causes of these diseases by studying genetic information and other factors in the collected samples. This is an ongoing effort to build a resource for future research.

Study design
This is an observational study aiming to enroll 10,000 participants. It involves collecting biological samples rather than testing a specific intervention.
What's involved
You would provide blood and/or tissue samples, which can be collected at the NIH Clinical Center, by your doctor, or by NIH staff off-site. Sample collection may involve a blood draw, cheek swab (buccal smear), or spitting into a cup (saliva collection).
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02543996

Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)

Recruiting
Not specifiedAges 1+Observational
National Heart, Lung, and Blood Institute (NHLBI)
~10,000 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To procure human biospecimens from affected and unaffected cohorts for on-going and future basic and translational research studies to identify underlying disease mechanism(s)
Measured over ongoing

Conditions

Undiagnosed Diseases
Cardiovascular Disease

Explore related trials

Cardiovascular DisorderRare DisorderUndiagnosed Diseases

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Manfred Boehm, M.D. · PRINCIPAL_INVESTIGATOR · National Heart, Lung, and Blood Institute (NHLBI)

Who to contact

William R Whalen, C.R.N.P.
[email protected]
(301) 402-9841
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age: older than 1 month of age
Affected pregnant women if they have been referred with a known or suspected pathology or if they become pregnant while on study.
Unaffected related pregnant women (including spouses/partners) for cord blood and tissue collection (surgical waste) only at the time of delivery.
Cognitively impaired individuals that are affected
Cognitively impaired individuals that are related to an affected subject.
Subjects willing to provide informed consent.

Exclusion

Healthy volunteers unable to give informed consent
Cognitively impaired individuals who are not affected
Cognitively impaired individuals who are not related to affected subjects.

What this trial measures

  • To procure human biospecimens from affected and unaffected cohorts for on-going and future basic and translational research studies to identify underlying disease mechanism(s)ongoing

    The primary objective is to procure human biospecimens from affected and unaffected cohorts for on-going and future basic translational research studies to identify underlying disease mechanism(s) and potential therapeutic approaches