Observational Study on Biomarkers in Infection
This study is looking at how well certain biological markers (biomarkers) can identify patients with infections like sepsis (a life-threatening response to infection) and inflammation who are at risk for poor outcomes. Researchers are interested in understanding how the body's immune system responds to infection. They are comparing current tests like white blood cell counts with other potential markers, including VEGF (Vascular Endothelial Growth Factor) and other inflammatory markers, to see if these can provide earlier and better information for doctors. The study aims to enroll 4200 participants, including adults aged 18 and older with confirmed or suspected infections, and a control group of adults without infection who have normal white blood cell counts and body temperature. The main goal is to see how these biomarkers relate to whether a patient dies in the hospital within 28 days of joining the study. The study's current recruitment status is unclear.
- Study design
- This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to include 4200 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 28 days after joining the study to assess in-hospital mortality.
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Biomarkers in Infection
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Nathan Shapiro, MD MPH · PRINCIPAL_INVESTIGATOR · Beth Israel Deaconess Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
What this trial measures
- 28 day in-hospital mortalitywithin 28 days after inclusion
participants will be followed up for 28 days