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Imaging for Abdominal Aortic Aneurysm (AAA) Biomechanical Properties

This study is looking at new ways to use imaging to understand the strength and flexibility of the aorta (the body's main artery) in people with and without an abdominal aortic aneurysm (AAA). An AAA is a bulge in the aorta. The study will use two special imaging techniques: ECHO (echocardiography, a type of ultrasound) and ECG-gated MRA (magnetic resonance angiogram, a type of MRI that uses an electrocardiogram to time the images). The goal is to see if these imaging methods can help predict things like aneurysm growth or rupture risk. You may be able to join if you are over 18 and have an AAA, or if you need aortic imaging for other reasons. The study aims to enroll 30 participants, but its current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive specific interventions (imaging). It plans to enroll 30 participants and will compare three groups: those under surveillance, those having open surgery, and those having endovascular aneurysm repair (EVAR).
What's involved
If you participate, your pre-operative MRA and ECHO studies will be modified to include ECG-gating with MRA and 2-Dimensional speckle-tracking ultrasound of the abdominal aorta. You will be followed for 1 year.
Compensation
Not stated in the trial record.
Follow-up
Participants in the study will be followed for 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02548546

Estimation of Biomechanical Aortic Wall Properties in Healthy and Aneurysmal Aortas Using Novel Imaging Techniques

Recruiting
NAAges 18+InterventionalDiagnostic
Mayo Clinic
~30 participants
Updated 2025-09-11 on ClinicalTrials.gov
What's tested:ECHOECG-gated MRA

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
ECHO Imaging
Measured over Change from baseline in ECHO imaging measurements

Conditions

Abdominal Aortic Aneurysm

Explore related trials

Abdominal Aortic Aneurysm

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Houssam Farres, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

Houssam Farres, MD
[email protected]
904-953-2077
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients \>18 years of age with ability to provide informed consent.
Patients with either symptomatic or asymptomatic AAA as defined by aortic diameter ≥ 1.5x normal diameter.
Patients with non-aneurysmal aortas who require aortic contrast imaging or echocardiography for preoperative planning or other reason.

Exclusion

Patients with contraindication to IV contrast such as allergy or severe kidney dysfunction.
Patients who do not require contrast imaging or echocardiogram as part of their care plan.
Terminally ill patients, and patients with estimated life expectancy of ≤ 6 months.
Patients unable to tolerate magnetic resonance imaging.

What this trial measures

  • ECHO ImagingChange from baseline in ECHO imaging measurements

    Imaging taken of the aneurysm, locating peak wall stress and measuring percent of strain per seconds.