Understanding Inflammation After Cardiac Arrest
This observational study is looking at how your body's immune system responds after a cardiac arrest. Researchers want to understand how inflammation (your body's response to injury or infection) and changes in metabolism (how your body uses energy) affect brain injury, survival, and recovery. They are particularly interested in how different types of white blood cells, like lymphocytes and neutrophils, behave. By studying blood samples taken over 7 days after cardiac arrest, they hope to find connections between these inflammatory responses and your clinical outcomes, including neurological (brain) and cardiac (heart) injury. This study is for adults aged 18 and older who have been admitted to the intensive care unit after a cardiac arrest and are unresponsive after resuscitation. The study is currently unclear on its recruitment status.
- Study design
- This is an observational study planning to include 400 participants. It is not testing a specific treatment but rather observing how the body responds after cardiac arrest.
- What's involved
- You would have blood samples taken during the 7 days following cardiac arrest. Your patient characteristics, clinical circumstances, and outcomes will also be recorded.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will look at correlations between inflammatory markers and clinical outcomes at 14 days, and neurological and cardiac injury biomarkers at 7 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Sergey Ryzhov, MD, PhD · PRINCIPAL_INVESTIGATOR · MaineHealth Institute for Research
- David B Seder, MD · PRINCIPAL_INVESTIGATOR · MaineHealth
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Correlations between inflammatory markers and clinical outcomes14 days
Correlations between inflammatory markers and clinical outcomes
- Correlations between inflammatory markers and biomarkers of neurological and cardiac injury7 days
Correlations between inflammatory markers and biomarkers of neurological and cardiac injury