AHPBA Pancreatic Irreversible Electroporation (IRE) Registry for Pancreatic Cancer

This study is creating a registry to better understand a treatment called Irreversible Electroporation (IRE) for pancreatic cancer. IRE is a procedure that uses electrical pulses to destroy cancer cells. The registry will collect information from 500 adult patients with pancreatic cancer who are eligible for this type of soft tissue ablation. The goal is to learn more about how doctors choose to use IRE, how well it works, and any side effects or complications. This information will help doctors provide the best care for patients needing surgical interventions for pancreatic cancer. You can join if you are an adult (18 or older) with pancreatic cancer and your doctor thinks you are a good candidate for soft tissue ablation. You cannot join if you have a pacemaker, certain metal implants near the tumor, or have had a heart attack recently.

Study design
This is an observational study, meaning researchers will collect information about patients who receive IRE treatment. It aims to include 500 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Adverse events will be measured for up to 5 years after treatment.

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NCT02674100

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

Recruiting
Not specifiedAges 18+Observational
University of Louisville
~500 participants
Updated 2025-02-25 on ClinicalTrials.gov
What's tested:Registry

At a glance

Recruiting sites
16 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adverse Events
Measured over Up to 5 years
Pancreatic Cancer
16 sites across 16 states
Alabama1
California1
Colorado1
Florida1
Georgia1
Kentucky1
Maryland1
New Jersey1
  • Robert Martin, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Louisville

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Eligibility criteria

Inclusion

Adult patients (greater than 18 years of age) diagnosed with pancreatic cancer that are eligible for soft tissue ablation per the treating physician.

Exclusion

Have a cardiac pacemaker or ICD implant
Non-removable implants with metal parts near target lesion
Myocardial infarction within 3 months prior to enrollment
Not suitable for general endotracheal anesthesia
  • Adverse EventsUp to 5 years

    Prospective collection of All Adverse Events that will be categorized as either IRE related or Non-IRE related and will be graded per CTCAE v4.0