NCT02695953

Neurobiology of Posttraumatic Stress Disorder Dysfunction and Recovery Following Cognitive Processing Therapy

Enrolling by Invitation
Not specifiedAges 18–55Observational
Milissa Kaufman
~130 participants
Updated 2026-06-25 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Potential Change in Evidence of PTSD symptoms with neuroimaging
Measured over Within 30 days before and again within 30 days after Cognitive Processing Therapy Treatment.
Posttraumatic Stress Disorder
1 sites across 1 states
Massachusetts1
  • Milissa L Kaufman, MD/PhD · PRINCIPAL_INVESTIGATOR · Mclean Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

PTSD diagnosis, as measured by the Clinician Administered PTSD Scale for DSM-5
history of chronic childhood trauma due to relational abuse
Ability to understand and sign informed consent
Enrollment in CPT program at McLean Hospital
Both genders, all ethnic backgrounds, age between 18 and 55
Fluent English speakers
Normal or Corrected Vision

Exclusion

History or current schizophrenia spectrum disorder or other psychotic disorders
History or current bipolar or other related disorders
Alcohol and/or substance use disorder within the past month
Metal implants
Medical or neurological illness (e.g., seizures, head injury in which they experienced a loss of consciousness)
Positive pregnancy test
  • Potential Change in Evidence of PTSD symptoms with neuroimagingWithin 30 days before and again within 30 days after Cognitive Processing Therapy Treatment.