This study is looking at low-dose total skin electron therapy (TSET) for people with mycosis fungoides (a type of skin lymphoma) that has either come back or didn't respond to previous treatments. This therapy uses high-energy electrons to target and shrink tumor cells on the skin. The treatment involves a "rotisserie technique" where you stand on a rotating platform while receiving TSET. Researchers hope this low-dose approach will be effective in killing tumor cells while causing fewer side effects, potentially allowing for repeated treatments if needed. The study will measure changes in your skin-related quality of life using a questionnaire called Skindex-29, and track how well your skin responds to treatment. To join, you must have biopsy-confirmed mycosis fungoides (stages IB-IIIA) with skin problems that haven't responded to at least one prior therapy, and a life expectancy of over 6 months. The current status of this study is unclear, and it plans to enroll 60 participants.

Study design

This is an observational study with a planned enrollment of 60 participants. The phase of the study is not specified.

What's involved

You would complete a Skindex-29 questionnaire and have your skin findings graded at the initial visit, then again at weeks 6 & 12, and every 3 months thereafter. You will also undergo standard of care low-dose total skin electron therapy for under 1 hour daily on days 10-21.

Compensation

Not stated in the trial record.

Follow-up

After treatment, you will be followed up at 6 and 12 weeks, and then every 3 months thereafter, for up to 3 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.