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NCT02757339

Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect

Enrolling by Invitation
Not specifiedAges 18–89Observational
Mclean Hospital
~200 participants
Updated 2026-06-25 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline correlates of traumatic dissociation in Functional Magnetic Resonance Imaging at 36 to 56 weeks
Measured over Baseline and 36 to 56 weeks after baseline

Conditions

Posttraumatic Stress Disorders
Dissociative Identity Disorder

Explore related trials

Dissociative Identity DisorderPost-Traumatic Stress Disorder

Where it's being run

1 sites across 1 states
Massachusetts1

Study leadership

  • Milissa L Kaufman, M.D./Ph.D · PRINCIPAL_INVESTIGATOR · Mclean Hospital

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Female
Clinical diagnosis of PTSD or DID and history of childhood abuse, or healthy controls
Age between 18 and 89
Legal and mental competency of the patient

Exclusion

Male
Under 18 or over 89
Legal or mental incompetence
Delirium secondary to medical illness
PTSD or DID due to general medical or neurological illness
History of neurological conditions that may cause significant psychiatric symptomatology (e.g., dementia)
Any contraindication to MR scans, including claustrophobia, pregnancy, metal implants, etc.
Current alcohol or substance dependence or abuse (within the last month)
A history of schizophrenia or other psychotic disorder
History of head injury or loss of consciousness for longer than 5 min (including concussion)

What this trial measures

  • Change from Baseline correlates of traumatic dissociation in Functional Magnetic Resonance Imaging at 36 to 56 weeksBaseline and 36 to 56 weeks after baseline

    Study participation will involve a baseline 60 minute cognitive assessment and a 60 minute Magnetic Resonance Imaging (MRI) at the 3 Tesla magnet in the McLean Hospital Imaging Center focusing on attention, emotion regulation, and symptoms of depersonalization. The first time point is baseline.The second time point will be 36-56 weeks after the baseline 60 minute Magnetic Resonance Imaging (MRI) scan at the 3 Tesla magnet in the McLean Hospital Imaging Center.