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Observational Study for Osteochondritis Dissecans of the Knee

This is an observational study for people diagnosed with osteochondritis dissecans (OCD) of the knee, a condition where a piece of bone and cartilage separates from the end of a bone. The study aims to understand how OCD progresses, what treatments are used, and how they affect patients over time, especially athletes. You can join if your OCD diagnosis is confirmed by an X-ray or MRI. There are no specific interventions or treatments being tested in this study; instead, researchers will simply collect information about your regular care. Success for this study means gathering valuable information from 3000 participants over many years to better understand OCD. The current recruitment status is unclear.

Study design
This is an observational study involving 3000 participants. It is not testing a new treatment, but rather collecting information about patients' experiences with osteochondritis dissecans.
What's involved
You will complete a medical history form and several questionnaires at your first visit. Mandatory surveys will also be collected at 2, 5, 10, and 25 years, and you can complete them at home if you can't return to the clinic.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 50 years, or until their OCD lesion is successfully healed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT02771496

Osteochondritis Dissecans of Knee Prospective Cohort

Recruiting
Not specifiedAll AgesObservational
University of Pennsylvania
~3,000 participants
Updated 2026-05-27 on ClinicalTrials.gov
What's tested:Other: observational only- no intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
IKDC questionnaire
Measured over baseline up to 50 years
+1 more outcome measured

Conditions

Osteochondritis Dissecans

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NCT02771496

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Pennsylvania

    Philadelphia, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • James L Carey, MD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania

Who to contact

Mounika Ponakala, MS
[email protected]
6093343767
Email the study team

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Eligibility criteria

Inclusion

Diagnosis of osteochondritis dissecans or focal articular cartilage defects as confirmed by x-ray or MRI

Exclusion

Non-confirmed diagnosis (i.e. patient does not yet have imaging confirmation)

What this trial measures

  • IKDC questionnairebaseline up to 50 years

    The primary outcome endpoint for this study is the patient's score on the IKDC Subjective questionnaire, or PEDI-IKDC Subjective questionnaire for patients under 18 years of age.

  • PEDI-IKDC questionnairebaseline up to 50 years

    The primary outcome endpoint for this study is the patient's score on the IKDC Subjective questionnaire, or PEDI-IKDC Subjective questionnaire for patients under 18 years of age.