Understanding Gender Differences in THC Effects
This study is looking at how Delta-9-Tetrahydrocannabinol (THC), the main active ingredient in cannabis, affects men and women differently. You might be able to join if you are a healthy adult between 18 and 55 years old, have used cannabis before, and are in good physical and mental health. However, you cannot join if you've never used cannabis, are experiencing major stress, or, for women, if you are taking estrogen supplements or birth control pills. Researchers will give participants either active THC or a placebo (a control substance with no THC). They will measure how "high" participants feel and test verbal learning to see the effects. The study aims to understand these differences, but the current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 100 participants. It compares the effects of active THC to a placebo.
- What's involved
- You would receive either active THC or a placebo. Researchers will measure your "high" at baseline, 10, 80, and 200 minutes after the THC infusion begins, and test your verbal learning 25 minutes after the infusion starts.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your "high" will be measured up to 200 minutes after the THC infusion begins, and verbal learning will be tested 25 minutes after the infusion begins.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Rewarding Effects measured by Visual Analog Scale (VAS)changes in "high" assessed over the following timepoints: baseline, +10, +80, and +200 minutes after THC infusion begins
subjective measure of THC induced "high"
- Verbal Learning: measured by Rey Auditory Verbal Learning Test (AVLT)25 minutes after THC infusion begins
measured as delay recall on the AVLT