Neurologic Stem Cell Treatment Study
This study is exploring a treatment for people with certain neurologic disorders, including those affecting the nervous system, neurodegenerative diseases, and stroke. The treatment involves using your own bone marrow derived stem cells (BMSC), which are special cells from your bone marrow. These cells are given to you through an IV (into a vein) and intranasally (into the lower part of your nose). Researchers want to see if this treatment can improve your neurologic function. To join, you must be at least 18 years old, have documented functional damage to your central or peripheral nervous system that isn't likely to improve with standard care, and be at least 6 months past the start of your disease. If you are on current medical therapy, you must be stable on that treatment. The study aims to enroll 500 participants.
- Study design
- This is an interventional study with a planned enrollment of 500 participants. The phase of the study is not specified.
- What's involved
- Participants will receive autologous bone marrow derived stem cells intravenously and intranasally. Neurologic function will be measured at 0, 1, 3, 6, and 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months after treatment to measure changes in neurologic function.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neurologic Stem Cell Treatment Study
At a glance
Conditions
Where it's being run
3 sites across 3 statesStudy leadership
- Steven Levy, MD · STUDY_CHAIR · MD Stem Cells
- Jeffrey Weiss, MD · PRINCIPAL_INVESTIGATOR · Coral Springs, Florida
Who to contact
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What this trial measures
- Change in Neurologic Function0,1,3,6 and 12 months
Neurologic function from prior to treatment (0 month) and the change in neurologic function at 1,3,6 and 12 months post treatment will be compared to pretreatment using the Neuro-QOL (Neurology Quality of Life) questionnaire. The scales of the Neuro-QOL assess the following Outcome Measures: Communication, Social Roles and Activities ,Anxiety , Depression, Emotional and Behavioral Dyscontrol, Lower Extremity Function (Mobility), Positive Affect and Well-Being, Sleep Disturbance, Upper Extremity Function ( Fine Motor, ADL/Activities of Daily Living) , Stigma , Satisfaction with Social roles and Activities, Cognitive Function. The scale for each question ranges from 1 to 5 with 1 being the most impairment and 5 being no impairment; higher numbers are better. The scale can range from 5 indicating no impairment to 45 for significant impairment. Each scale will be recorded and presented as separate Outcome Measurements.