Gender Differences in Dronabinol Effects Study
This study is looking at how a cannabis-related medication, Dronabinol (10 mg capsule), affects men and women differently. Researchers want to understand the immediate effects of Dronabinol and why these differences might occur. You might be able to join if you are between 18 and 55 years old, have used cannabis before, and are in good physical and mental health. However, you cannot join if you've never used cannabis, are experiencing major stress, or for women, if you are taking estrogen supplements or birth control pills. The study will measure how Dronabinol affects feelings of being "high" and your verbal learning abilities. The current recruitment status is unclear.
- Study design
- This interventional study plans to enroll 40 participants to compare the effects of Dronabinol versus a placebo pill.
- What's involved
- Participants will receive either Dronabinol or a placebo. Measurements for "high" feelings will be taken over several hours, and verbal learning will be tested at baseline and 80 minutes after taking the medication.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for rewarding effects are taken up to 300 minutes (5 hours) after administration, and verbal learning up to 80 minutes.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Change from Baseline: Rewarding Effects measured by Visual Analog Scale (VAS)changes in "high" assessed over the following timepoints: baseline, +60, +80, +120, +180, +300 minutes after start of oral Dronabinol administration.
Subjective measure of THC induced "high"
- Change from Baseline: Verbal Learning: Measured by Rey Auditory Verbal Learning Test (RAVLT)baseline and +80 minutes after start of oral Dronabinol administration.
Measured as delay recall on the AVLT