This study is looking into how certain signals, specifically the epidermal growth factor (EGF) family and Neuregulin-1β (NRG), affect cells in the human heart. These signals are important for heart development and health. Researchers want to understand how these signals regulate a specific type of cell in the adult heart that responds to EGF and NRG. You may be able to participate if you are an adult with severe coronary artery disease who is scheduled for coronary artery bypass surgery. The study will measure the number of highly proliferative (fast-growing) cells isolated from heart tissue within 14 days. The current status of this study is unclear, and it plans to enroll 80 participants.

Study design

This is an observational study with a planned enrollment of 80 participants. It is not specified if it is randomized or blinded.

What's involved

If you participate, a small biopsy will be taken from your heart during your scheduled coronary artery bypass surgery. The cells from this biopsy will then be analyzed in a laboratory.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at up to 14 days from cell isolation, which suggests a short follow-up period for the lab analysis.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.