Advanced Fetal Imaging - Phase II

This study, called Advanced Fetal Imaging - Phase II, is testing a new investigational MRI coil designed specifically for pregnant women. This special coil is part of the MRI machine and is placed over the body part being imaged. The goal is to see if this new coil, along with new MRI techniques, can create clearer and more reliable fetal MRI images compared to the standard MRI images currently used. You could join if you are a pregnant woman between 18 and 45 years old, with a healthy pregnancy or if there's a concern about your baby or placenta that would typically lead to a fetal MRI. The study aims to enroll 300 participants, but its current recruitment status is unclear.

Study design
This interventional study plans to enroll 300 pregnant women to evaluate a new investigational MRI coil.
What's involved
You would participate in an MRI scan, which includes a 60-minute full research MRI scan and potentially an additional 15-minute MRI scan.
Compensation
Not stated in the trial record.
Follow-up
The quality of the research fetal MRI images will be compared to standard images for up to 41 months (July 2016-December 2019).

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NCT02840019

Advanced Fetal Imaging - Phase II

Recruiting
NAAges 18–45InterventionalDiagnostic
Boston Children's Hospital
~300 participants
Updated 2025-12-08 on ClinicalTrials.gov
What's tested:Investigational MRI coil designed for pregnant womenMRI Scan

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Research fetal MRI image quality compared to standard clinical fetal MRI image quality
Measured over July 2016-December 2019, up to 41 months
Pregnancy
1 sites across 1 states
Massachusetts1
  • P. Ellen Grant, MD · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

60 Minute Full Research MRI Scan:
Gestational age between 18 and 40 weeks
AND
Pregnant women with a healthy pregnancy
OR
Pregnant women with a concern for fetal/placental abnormalities referred for a clinical fetal MRI by their obstetrician
OR
Pregnant women with a concern for fetal/placental abnormalities NOT referred for a clinical fetal MRI by their obstetrician
15 Minute Add-On Research Scan:
Gestational age between 18 and 40 weeks
AND
Pregnant women with a concern for fetal abnormalities referred for a clinical fetal MRI by their obstetrician
AND
The clinical fetal MRI will occur at Boston Children's Hospital

Exclusion

Pregnant women with a contraindication to MRI (implanted metal, non-removable piercings, pacemaker, etc)
Pregnant women who are claustrophobic
Pregnant women who are medically unstable for an MRI
  • Research fetal MRI image quality compared to standard clinical fetal MRI image qualityJuly 2016-December 2019, up to 41 months

    Research fetal MRI image quality will be compared to the standard clinical fetal MRI image quality.