NCT02914951

Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability

Enrolling by Invitation
NAAges 8–16InterventionalTreatment
Yale University
~6 participants
Updated 2026-05-08 on ClinicalTrials.gov
What's tested:Cognitive-Behavioral TherapyFunctional magnetic resonance imaging (fMRI)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Modified Overt Aggression Scale (MOAS)
Measured over Weekly - up to 20 weeks
+1 more outcome measured
Autism
Intellectual Disability

NCT02914951

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Yale Child Study Center

    New Haven, Connecticutno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Denis Sukhodolsky, PhD · PRINCIPAL_INVESTIGATOR · Associate Professor

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

DSM-5 diagnosis of Autism Spectrum Disorder
Presence of disruptive behaviors such as irritability and anger outbursts
IQ between 55 and 85
ABC Irritability Scale score greater than or equal to 15
Un-medicated or on stable medication regimen
Able to complete all study assessment and fMRI procedures

Exclusion

Medical or psychiatric condition that would require alternative treatment
  • Modified Overt Aggression Scale (MOAS)Weekly - up to 20 weeks

    Modified Overt Aggression Scale (MOAS) is a 16-item scale that reflects the frequency and severity of incidents of aggressive behavior

  • Aberrant Behavior Checklist - Irritability Scale (ABC-I)Weekly - up to 20 weeks

    The ABC-I is a 15-item parent rating of irritability that has been commonly used in clinical trials in children with ASD.