Warfarin Dosing in Hispanic and Latino Patients

This observational study is looking at how genetics affect the right dose of warfarin, a blood thinner used to prevent and treat blood clots. Warfarin doses need to be carefully managed to avoid bleeding or new clots. Researchers want to understand why some Hispanic and Latino patients need different warfarin doses by studying their genes. The study aims to identify factors that predict a stable warfarin dose. To join, you must be at least 18 years old, identify as Hispanic or Latino, and already be on a stable warfarin dose. The study is planning to enroll 400 participants, but its current status is unclear.

Study design
This is an observational study with no specified phase, planning to enroll 400 participants. It is not a randomized or blinded study.
What's involved
You would provide a mouthwash sample or a blood sample (if you are already having blood drawn for a regular appointment).
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, stable warfarin dose, is measured at the time of enrollment. No further follow-up is specified.

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NCT02972385

Pharmacogenomics of Warfarin in Hispanics and Latinos

Recruiting
Not specifiedAges 18+Observational
University of Arizona
~400 participants
Updated 2024-06-27 on ClinicalTrials.gov
What's tested:Mouthwash sampleBlood Draw

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Stable warfarin dose
Measured over At time of enrollment
Thrombosis
Hemorrhage
1 sites across 1 states
Arizona1

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Eligibility criteria

Inclusion

At least 18 years of age
Ability to give informed consent
Therapeutic INR for at least 2 consecutive clinic visits
Self-identifies as Hispanic or Latino

Exclusion

Less than 18 years old
Unable to give informed consent
Severe hepatic impairment
  • Stable warfarin doseAt time of enrollment

    Dose of warfarin required to maintain stable INR for at least 2 consecutive clinic visits.