Diffusion MRI in Heart Failure Study
This study is investigating how changes in the heart's structure contribute to heart failure. Researchers are using Diffusion Tensor MRI (DTI), which measures water movement in the heart to understand muscle fiber orientation, and Gadolinium DOTA Meglumine, a contrast agent, to get detailed images. They hope to understand how heart failure develops and progresses. You might be able to join if you are a healthy adult, or if you've recently had a heart attack (myocardial infarction) and are stable, or if you've experienced heart failure in the last year and have left ventricular hypertrophy (thickening of the heart's main pumping chamber). The main goal is to measure the heart's muscle fiber angle after 12 months. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 160 participants. It involves using specific imaging techniques to understand heart structure.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 12 months, suggesting participants will be followed for at least that long.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Diffusion MRI in Heart Failure
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- David E. Sosnovik, MD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
What this trial measures
- Myofiber Helix Angle12 months
The investigators aim to determine how the myofibers in the heart change their orientation in heart disease by measuring their helix angle.