Progesterone for Preeclampsia Before 34 Weeks
This study is looking at whether giving 17-hydroxyprogesterone caproate (17 OHPC) can improve outcomes for mothers and babies when preeclampsia is diagnosed early in pregnancy (before 34 weeks). Preeclampsia is a serious pregnancy complication characterized by high blood pressure and signs of damage to another organ system, most often the liver and kidneys. You may be able to join if you are a woman between 18 and 45 years old, are pregnant with preeclampsia between 23 and 34 weeks gestation, and are a patient at UMMC. The study aims to see if this treatment leads to better health for both mother and baby. The current status of this study is unclear, and it plans to enroll 60 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 60 women.
- What's involved
- If you join, you will receive 17 OHPC injections at admission and every 7 days. Blood samples will be taken at various times until after delivery, and your placenta will be collected after birth.
- Compensation
- Not stated in the trial record.
- Follow-up
- Information about the mother and newborn will be collected while in the hospital and until discharge.
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Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Babbette LaMarca, PhD · PRINCIPAL_INVESTIGATOR · University of Missisippi Medical Center
- Sheila S Belk · STUDY_DIRECTOR · UMMC Pharmacology and Toxicology
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Improvement of maternal and perinatal outcomesBaseline
Assessment of maternal BP trends