Observational Study of Lung Cancer Genetics

This study is looking at the genes of people with lung cancer and healthy individuals to understand how genetics might affect lung cancer risk and survival. Researchers are not testing any new drugs or treatments. They are studying how genetic differences (SNPs) are linked to lung cancer and how these differences might impact how well treatments work at various stages of the disease. The goal is to find factors that can predict how the disease will progress and how long people will live. You can join if you are 18 or older and either have lung cancer confirmed by a doctor or are a healthy person without any cancer. The study aims to enroll 15,000 participants. The current recruitment status is unclear.

Study design
This is an observational study with a case-control design, meaning researchers will compare people with lung cancer to healthy individuals. It plans to include 15,000 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' survival will be monitored for 20 years using questionnaires and medical records.

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NCT03029325

Molecular and Genetic Analysis of Lung Cancer

Recruiting
Not specifiedAges 18+Observational
Massachusetts General Hospital
~15,000 participants
Updated 2024-11-29 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Survival among patients at different stages of lung cancer and treatment will be measured using questionnaires along with medical chart data to monitor treatment and disease progression
Measured over 20 years
Lung Cancer
1 sites across 1 states
Massachusetts1
  • David C Christiani, MD · PRINCIPAL_INVESTIGATOR · Harvard TH Chan School of Public Health

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Eligibility criteria

Inclusion

healthy controls: participants without evidence of any cancer
cases: pathology proven primary lung cancer

Exclusion

younger than 18 years old
  • Survival among patients at different stages of lung cancer and treatment will be measured using questionnaires along with medical chart data to monitor treatment and disease progression20 years

    Study lung cancer development in a case control study. We will look at three separate outcome measures specified below