This observational study is looking at the relationship between brain changes and genetic factors in people with laryngeal dystonia (also called spasmodic dysphonia). Researchers will use MRI scans (magnetic resonance imaging, a way to look inside the body) of the brain and collect blood samples for genetic studies. They hope to identify brain markers that can help tell the difference between different types of laryngeal dystonia, predict its development, and confirm related gene mutations. You may be able to join if you have laryngeal dystonia (adductor or abductor, familial or sporadic), voice tremor (essential or dystonic), or muscle tension dysphonia. The study aims to enroll 410 participants, but its current status is unclear.

Study design

This is an observational study with a planned enrollment of 410 participants. It is not a treatment study and does not involve different treatment groups.

What's involved

You would undergo functional and structural MRI scans of your brain and have blood samples collected for genetic studies.

Compensation

Not stated in the trial record.

Follow-up

Brain changes in laryngeal dystonia will be measured at 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.