Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers

This study aims to create a public database of full-body X-ray images from healthy volunteers using a special low-dose X-ray system called EOS imaging. Researchers want to understand how the skeleton changes naturally as people age, by looking at measurements like spinal curves (coronal plumb-line, sagittal vertebral axis, external auditory meatus plumb-line). This information will help doctors better understand what a "normal" spine looks like at different ages and guide decisions for spinal surgeries. You can join if you are between 21 and 85 years old and have not had spine surgery. The study plans to enroll 60 people, and its current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 60 participants. It aims to create a database of full-body X-ray images from healthy volunteers.
What's involved
You would undergo one EOS imaging scan of your whole body skeletal structure, which takes about 20 minutes.
Compensation
Not stated in the trial record.
Follow-up
Measurements for the primary endpoints are taken during the single EOS scan, which lasts 20 minutes.

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NCT03076658

Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers

Recruiting
NAAges 21–85InterventionalDiagnostic
University of Colorado, Denver
~60 participants
Updated 2023-09-28 on ClinicalTrials.gov
What's tested:EOS imaging

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Coronal plumb-line
Measured over Through 1 EOS scan, 20 minutes
+14 more outcomes measured
Intervertebral Disc Degeneration
Osteoarthritis, Spine
1 sites across 1 states
Colorado1
  • Christopher Kleck, MD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

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Eligibility criteria

Inclusion

Males and females age 21-85 without a history of spine surgery.

Exclusion

History of spine or neural axis surgery
History of cancer with or without metastatic disease
Connective tissue, rheumatologic (or other inflammatory arthropathies), or neurologic disorders
History of knee replacement surgery, as these may have contractures causing unexpected changes in alignment
Severe osteoarthritis of the hips/knees/ankles
Spondylitis
Compression fractures or other trauma of the spinal column
Previous trauma/fractures of the pelvis whether or not surgery was required
Previous trauma or fractures of the lower extremities requiring surgery
Pregnant women
BMI \>37
Oswestry Disability Index score \>25
  • Coronal plumb-lineThrough 1 EOS scan, 20 minutes
  • Sagittal vertebral axis (SVA)Through 1 EOS scan, 20 minutes
  • External auditory meatus plumb-lineThrough 1 EOS scan, 20 minutes
  • Cervical lordosisThrough 1 EOS scan, 20 minutes
  • Thoracic kyphosisThrough 1 EOS scan, 20 minutes
  • Lumbar lordosisThrough 1 EOS scan, 20 minutes
  • Hip flexion/extensionThrough 1 EOS scan, 20 minutes
  • Knee flexion/extensionThrough 1 EOS scan, 20 minutes
  • Ankle flexion/extensionThrough 1 EOS scan, 20 minutes
  • T1 tiltThrough 1 EOS scan, 20 minutes
  • T1 spino-pelvic instanceThrough 1 EOS scan, 20 minutes
  • Acetabular indexThrough 1 EOS scan, 20 minutes
  • Pelvic tilt (PT)Through 1 EOS scan, 20 minutes
  • Pelvic incidence (PI)Through 1 EOS scan, 20 minutes
  • Sacral slope (SS)Through 1 EOS scan, 20 minutes