Blood Flow Restriction Training for Quadriceps Function After Arthroscopic Knee Surgery

This study is looking at whether adding blood flow restriction (BFR) training to physical therapy (PT) helps improve quadriceps (thigh muscle) function after arthroscopic knee surgery, specifically for those who have had an ACL (anterior cruciate ligament) reconstruction. Researchers want to see if PT with BFR training is better than PT alone at preventing muscle loss and improving strength and function. They will measure changes in quadriceps muscle size using ultrasound at different times after starting PT. You might be able to join if you are between 14 and 55 years old, have had an ACL reconstruction, and plan to return to sports. The study aims to enroll 150 participants, but its current recruitment status is unclear.

Study design
This interventional study plans to enroll 150 participants to compare physical therapy with blood flow restriction training to physical therapy alone.
What's involved
Participants will attend two or three 90-minute physical therapy sessions per week for 6 weeks, with a minimum of 18 visits required. Quadriceps muscle size will be measured at the start of PT, and then 1, 2, and 5 months later.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 5 months after the start of physical therapy to measure changes in quadriceps muscle size.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03096366

Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?

Recruiting
NAAges 14–55InterventionalTreatment
The University of Texas Health Science Center, Houston
~150 participants
Updated 2022-05-04 on ClinicalTrials.gov
What's tested:Blood flow restrictionPhysical therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Quadriceps Muscle Cross-Sectional Area (CSA) as Assessed by Ultrasound
Measured over at start of PT, 1 month after start of PT
+2 more outcomes measured
Quadriceps Atrophy
ACL Reconstruction

NCT03096366

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • The University of Texas Health Science Center at Houston

    Houston, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Walter R Lowe, MD · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center, Houston

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Eligibility criteria

Inclusion

Anterior cruciate ligament (ACL) reconstruction with concomitant meniscus or cartilage restoration procedures
Adherence to modified weight bearing status before initiation of PT
Expected participation in recreational or competitive sports after release to full activities

Exclusion

Unable to attend (or participate in) physical therapy
Pregnancy
Malignancy
Fracture
Peripheral vascular disease
History of deep vein thrombosis (DVT)
  • Change in Quadriceps Muscle Cross-Sectional Area (CSA) as Assessed by Ultrasoundat start of PT, 1 month after start of PT

    Initiation of PT is 1 month after surgery

  • Change in Quadriceps Muscle Cross-Sectional Area (CSA) as Assessed by Ultrasoundat start of PT, 2 months after start of PT

    Initiation of PT is 1 month after surgery

  • Change in Quadriceps Muscle Cross-Sectional Area (CSA) as Assessed by Ultrasoundat start of PT, 5 months after start of PT

    Initiation of PT is 1 month after surgery