This study is looking at how well islet cells (cells that make insulin) work after they are transplanted into people with chronic pancreatitis. Researchers will collect blood samples to analyze inflammatory markers (signs of inflammation) and how well the transplanted islet cells are functioning. They are interested in people with chronic pancreatitis who are having a total pancreatectomy (removal of the whole pancreas) with or without autologous islet transplantation (TP-AIT, where your own islet cells are transplanted back into you). The main goal is to understand islet graft function one year after the transplant. You can join if you are 18 or older, have chronic pancreatitis, and can attend follow-up visits at Baylor.

Study design

This is an observational study involving 100 participants. 85 participants will have TP-AIT and 15 will have TP alone.

What's involved

You will need to attend required follow-up visits at Baylor. Blood samples will be collected.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for one year after islet cell transplantation to analyze graft function.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.