Tesamorelin for Peripheral Nerve Injury Recovery
This study is looking at whether a drug called Tesamorelin can help people recover better after a peripheral nerve injury. Tesamorelin works by increasing growth hormone, which has been shown to help nerves heal in animal studies. You could be eligible if you are an adult (18 or older) with an ulnar nerve (a nerve in your arm) laceration (a cut) at the wrist that has been repaired. However, you cannot participate if you have certain cancers, uncontrolled diabetes or high blood pressure, specific pituitary gland problems, are pregnant, or have drug or alcohol dependence. The main goal is to see if Tesamorelin improves your hand function, specifically your pinch strength, after 12 months. The study is currently recruiting 36 participants.
- Study design
- This is a randomized, double-blinded study, meaning participants are randomly assigned to receive Tesamorelin or no treatment, and neither you nor the study staff will know which you are receiving. There will be 36 participants in total.
- What's involved
- You would have 12 monthly follow-up visits over a year. During these visits, you will have clinical exams, nerve tests (electrodiagnostic studies), and fill out questionnaires.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your recovery will be assessed for 12 months after starting the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury
At a glance
Conditions
NCT03150511
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Sami Tuffaha
Baltimore, Marylandstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Sami Tuffaha, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- 3-point chuck pinch test12 months
Pinch strength measure as measured by a pinch gauge.