Non-invasive Nerve Stimulation for PTSD and Sleep

This study is looking at how a non-invasive nerve stimulation device, called transcutaneous electrical nerve stimulation, might help improve sleep for veterans with Post-Traumatic Stress Disorder (PTSD) and/or a history of mild Traumatic Brain Injury (TBI). The goal is to see if this stimulation can change the quality of your sleep, measured over up to 8 hours. You might be able to join if you are a veteran between 18 and 55 years old with PTSD, with or without a history of mild TBI. However, you cannot participate if you have severe psychiatric illness not related to PTSD or TBI, other serious medical conditions that affect thinking, current drug abuse, or a breathing disorder requiring constant oxygen. The study aims to enroll 221 participants, but its current status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 221 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your physiological sleep architectural quality will be measured for up to 8 hours.

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NCT03170440

Non-invasive Nerve Stimulation for PTSD and Sleep

Recruiting
NAAges 18–55InterventionalBasic science
University of Florida
~221 participants
Updated 2025-07-01 on ClinicalTrials.gov
What's tested:Transcutaneous nerve stimulation location 1

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Physiological sleep architectural quality
Measured over up to 8 hours
Post Traumatic Stress Disorder
Traumatic Brain Injury
3 sites across 1 states
Florida3
  • John Williamson, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Florida

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Eligibility criteria

Inclusion

veterans with history of PTSD with and without history of mild TBI

Exclusion

history of severe psychiatric illness unrelated to PTSD or TBI
other medical conditions of severity that may impair cognition
current illicit or prescription drug abuse
breathing disorder requiring constant use of oxygen
  • Physiological sleep architectural qualityup to 8 hours

    Polysomnography