This study aims to find early signs of Necrotizing Enterocolitis (NEC), a serious gut condition, in premature and low birth weight babies. Researchers will observe infants in the Neonatal Intensive Care Unit (NICU) to see if non-invasive measurements and certain markers in the body can predict NEC before symptoms appear. The goal is to identify babies at risk early so that future treatments can be developed to prevent the disease from getting worse. You might be eligible if your baby was born at 30 weeks gestation or less, or weighed 1500 grams or less at birth. The study is looking to enroll up to 450 infants, with a focus on comparing babies who develop NEC with healthy controls. The main thing being measured is splanchnic tissue oxygenation, which is the oxygen level in the gut.

Study design

This is an observational study, meaning researchers will watch and collect information without giving any specific treatments. It plans to enroll up to 450 premature and low birth weight infants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, splanchnic tissue oxygenation, will be measured in 2026.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.