Observational Study on Gut Changes After Campylobacter Infection

This study is looking at how your gut (gastrointestinal or GI) lining and the bacteria in your gut change after an infection with Campylobacter. Some people who get this infection later develop long-term gut problems like Irritable Bowel Syndrome (IBS). Researchers want to see if these early changes in your gut can help predict who might be at risk for developing IBS. You can join if you are between 18 and 80 years old, have not had certain abdominal surgeries, and have a confirmed Campylobacter infection. The main goal is to see if you develop IBS within 6 months after your infection.

Study design
This is an observational study, meaning researchers will watch for changes without providing any specific intervention. It plans to enroll 150 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months to see if they develop Irritable Bowel Syndrome (IBS).

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NCT03223077

Mucosal and Microbiota Changes During Acute Campylobacteriosis

Recruiting
Not specifiedAges 18–80Observational
Mayo Clinic
~150 participants
Updated 2026-08-07 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Development of IBS is the endpoint.
Measured over 6 months
Irritable Bowel Syndrome
1 sites across 1 states
Minnesota1
  • Madhusudan Grover, MBBS · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Inclusion

No abdominal surgery (except appendectomy and cholecystectomy)
Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter

Exclusion

History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease.
History of gastroenteritis in six months prior to Campylobacter enteritis
Pregnancy
  • Development of IBS is the endpoint.6 months

    Number of Subjects Who Develop Irritable Bowel Syndrome After Campylobacter Infection