Comparing Ropivacaine Infusions for Post-Surgical Pain

This study is looking at different ways to give medicine for pain after surgery. It compares two methods of giving ropivacaine, a local anesthetic (pain-numbing medicine), through a catheter (a thin tube placed near nerves). One method is a continuous infusion, where the medicine flows constantly. The other is a scheduled intermittent bolus, where you get doses at set times. The main goal is to see which method works better at reducing your pain after surgery, specifically on days 0, 1, and 2. You might be able to join if you are an adult having a nerve block for post-operative pain and are generally healthy (ASA physical status I, II, or III). We are looking to enroll 240 participants in total.

Study design
This interventional study plans to enroll 240 participants across three groups, each focusing on a different nerve block site.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your pain will be measured on the day of surgery (day 0) and for two days afterward (days 1 and 2).

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NCT03230565

Continuous Infusions vs Scheduled Bolus Infusions

Recruiting
PHASE4Ages 18+InterventionalTreatment
Stanford University
~240 participants
Updated 2025-12-08 on ClinicalTrials.gov
What's tested:Ropivacaine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Post-surgical pain
Measured over Post-operative day 0, 1, and 2
Surgical Procedure, Unspecified
Pain, Postoperative
1 sites across 1 states
California1
  • Jean Louis-Horn, MD · PRINCIPAL_INVESTIGATOR · Stanford University

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Eligibility criteria

Inclusion

Adult patients presenting for nerve block catheters for post-operative analgesia
ASA physical status I, II, or III.

Exclusion

Pregnancy
Incarceration
Age \<18
BMI \>35
Pre-operative opioid use \>30 mg morphine equivalents per day
Inability to communicate with investigators by telephone
Pre-existing neuropathy of the operative extremity.
  • Post-surgical painPost-operative day 0, 1, and 2

    Pain scores will be collected using a Numeric Rating Scale (NRS) from 0-10, where 0 is the lowest and 10 is the highest pain level.