This observational study is looking for people aged 50 to 90 who have a strong family history of pancreatic cancer or certain genetic mutations (like BRCA1, BRCA2, ATM, PALB2, or CDKN2A). The main goal is to find pancreatic cancer or early warning signs (precursor lesions) at an early stage. You would receive annual MRI/MRCP (Magnetic Resonance Imaging/Magnetic Cholangiopancreatography) scans, which use magnets and radio waves to create detailed pictures of your pancreas. Researchers are also collecting blood samples to help develop a new blood test for pancreatic cancer. The current recruitment status is unclear.

Study design

This is an observational study with a planned enrollment of 200 participants. It is not a randomized study.

What's involved

You would have a psychological survey and donate blood every 6 months for 3 years. You would also receive an MRI scan annually for 3 years (a total of 4 scans).

Compensation

The costs of the MRI scans will be covered by the study. Other compensation is not stated in the trial record.

Follow-up

The primary endpoint, looking for early stage pancreatic cancer or precursor lesions, is measured through study completion, up to 3 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.