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Observational Study for Cardiopulmonary and Vascular Disease Research

This is an observational study collecting samples like blood and urine to help researchers understand genes, proteins, sugars, fats, vitamins, and other substances in your body. The goal is to develop new lab tests and further research into conditions affecting the heart and lungs, such as endothelial dysfunction (problems with the inner lining of blood vessels), inflammation, arteriosclerosis (hardening of the arteries), and pulmonary hypertension (high blood pressure in the lungs). This study is looking for both healthy volunteers and individuals aged 18 to 100 years old who have diseases related to the cardiovascular system, inflammation, or endothelial dysfunction. The success of this study will be measured by the development of new lab tests over 10 years.

Study design
This is an observational study planning to enroll 1000 participants. It is not testing a specific intervention or drug.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary goal of developing new lab tests will be measured at 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03253705

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Recruiting
Not specifiedAges 18+Observational
National Institutes of Health Clinical Center (CC)
~1,000 participants
Updated 2026-08-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Exploratory assay development
Measured over 10 years

Conditions

Endothelial Dysfunction
Inflammation in Cardiopulmonary and Vascular Disease States
Healthy Volunteers

Explore related trials

ArteriosclerosisCardiovascular DisorderEndothelial dysfunctionHealthyInflammationPulmonary Hypertension

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Michael A Solomon, M.D. · PRINCIPAL_INVESTIGATOR · National Institutes of Health Clinical Center (CC)

Who to contact

Grace M Graninger, R.N.
[email protected]
(301) 496-9320
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Exclusion

For critically ill patients with shock (on vasopressors), no more than 20mL of blood may be obtained within a 24 hour period. (No more than 200ml over eight weeks.)

What this trial measures

  • Exploratory assay development10 years

    Development of new assays