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Recruiting Healthy Volunteers for NIMH Research Studies

This observational study aims to find healthy adult volunteers for future research at the National Institute of Mental Health (NIMH) in Bethesda, Maryland. The study will create a list of healthy individuals and develop a set of normal brain MRI scans linked to their characteristics. This information will be shared with other researchers to help advance scientific understanding. To join, you must be between 18 and 70 years old, in good general health, and able to read and understand English. The study is currently recruiting participants, with a goal of 2000 volunteers. Success will be measured by collecting demographic data, medical history, and various psychological, emotional, and cognitive assessments, including physical exams or MRI findings.

Study design
This is an observational study with a planned enrollment of 2000 participants. It involves two parts: an online screening followed by an in-person assessment at the NIH Clinical Center.
What's involved
You would first complete online forms to check your eligibility. If eligible, you would have an in-person assessment at the NIH Clinical Center, which may include optional MRI brain scans, MEG recordings, and EKG.
Compensation
Not stated in the trial record.
Follow-up
Assessments for this study are measured at ongoing intervals, indicating continuous data collection rather than a fixed follow-up period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03304665

Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies

Recruiting
Not specifiedAges 18–70Observational
National Institute of Mental Health (NIMH)
~2,000 participants
Updated 2026-09-01 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Online self-report and in-person assessments that may yield demographic data, mental and medical history and symptoms, results of measures of psychological, emotional, physiologic, biological, and cognitive functioning, and physical or MRI findi...
Measured over Ongoing

Conditions

Healthy Volunteer

Explore related trials

Healthy Volunteer

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Carlos A Zarate, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Mental Health (NIMH)

Who to contact

Carlos A Zarate, M.D.
[email protected]
(877) 646-3644
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

18 - 70 years of age.
Able to read, speak, and understand English.
Able to provide informed consent.
In current good general health.

Exclusion

Have a history of significant or unstable medical or mental health condition requiring treatment, such as heart or lung disease, depression or psychosis.
Endorse current self-injury, suicidal thoughts or behavior.
Have current illicit drug use by history or urine drug screen.
Are found to have an abnormal physical exam or laboratory result that may require treatment or further evaluation.
Less than an 8th grade education.
Pregnancy.
Positive HIV test as HIV positivity has been associated with neurological changes.
Metal in body which would make having an MRI scan unsafe.
Being uncomfortable in small, closed spaces such as the MRI machine.
Inability to lie comfortably on back for at least 45 minutes.
Pregnancy.
Metal in body which would cause artifacts on MEG recordings.

What this trial measures

  • Online self-report and in-person assessments that may yield demographic data, mental and medical history and symptoms, results of measures of psychological, emotional, physiologic, biological, and cognitive functioning, and physical or MRI findi...Ongoing

    Online self-report and in-person assessments that may yield demographic data, mental and medical history and symptoms, results of measures of psychological, emotional, physiologic, biological, and cognitive functioning, and physical or MRI findings.