CPAP for Supine Hypertension in Autonomic Failure
This study is looking at whether continuous positive airway pressure (CPAP) can help lower high blood pressure (supine hypertension) in people with autonomic failure. Supine hypertension is a common problem in autonomic failure, where blood pressure gets too high when lying down. CPAP is a device that uses mild air pressure to keep airways open, often used for sleep-related breathing issues. Researchers want to see if using CPAP at night can reduce your blood pressure. To join, you need to be between 18 and 85 years old, have autonomic failure and supine hypertension, and not have certain other health conditions like heart failure or serious allergies. The main goal is to measure your supine systolic blood pressure after 12 hours of CPAP use. The study is currently unclear on its recruitment status and plans to enroll 12 participants.
- Study design
- This is an interventional study planning to enroll 12 participants. It will test continuous positive airway pressure (CPAP) against a placebo.
- What's involved
- You would use a CPAP device during the night, starting at 8 PM. The CPAP level will be determined during an initial test.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, supine systolic blood pressure, is measured at 12 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treatment of Supine Hypertension in Autonomic Failure (CPAP)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Italo Biaggioni, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Supine Systolic Blood Pressure12 hours
change in supine systolic blood pressure from baseline