This study is looking at whether treating inflammation in the esophagus (the tube that connects your mouth to your stomach) can improve how stretchy it is. This condition, called Eosinophilic Esophagitis, involves too many immune cells (eosinophils) in the esophagus. Researchers will use a diagnostic test called endoflip to measure the stretchiness of your esophagus before and after a two-month course of high-dose proton pump inhibitors (PPIs). They hope to see an improvement in how stretchy your esophagus is, which could also help with swallowing difficulties. The study plans to enroll 10 participants between 18 and 65 years old who have been diagnosed with eosinophilia in their esophagus. The current status of this study is unclear.

Study design

This is an observational study with a planned enrollment of 10 participants. It is not specified if it is randomized or blinded.

What's involved

You would receive a two-month course of high-dose proton pump inhibitors. Your esophageal distensibility will be measured before and after this treatment using endoflip.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at 2 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.