Observational Study on OCD Biomarkers Using Behavioral Tasks
This study is looking for biological markers (biomarkers) that can help us understand obsessive-compulsive disorder (OCD) better. Researchers will use two types of behavioral tasks: the Beads Task, which involves making decisions about rewards, and PROVOC Tasks, where you'll be exposed to triggers you usually avoid. During these tasks, researchers will measure your brain activity using EEG (a test that records brain waves) and film your facial reactions. This will help them find changes that could be biomarkers for OCD. You might be able to join if you are 18 to 65 years old, have an OCD diagnosis, and meet other specific health criteria. The study aims to find these biomarkers to help develop new ways to understand and treat OCD.
- Study design
- This is an observational study, meaning participants will not receive a new treatment, but will be observed during tasks. It plans to enroll 20 participants.
- What's involved
- You will participate in a clinical interview on Day 1 (4 hours or less) and complete behavioral tasks with EEG on Day 2 (2.5 hours or less).
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoints, which are the main things being measured, are assessed on Day 2.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Locating Biomarkers in OCD Through Behavioral Tasks
At a glance
Conditions
Where it's being run
3 sites across 3 statesStudy leadership
- Wayne Goodman, MD · PRINCIPAL_INVESTIGATOR · Baylor College of Medicine
Who to contact
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Do you actually qualify for this trial?
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Inclusion
What this trial measures
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - Beads taskDay 2
Subject will perform beads task while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - PROVOC Task 1Day 2
Subject will undergo PROVOC Task 1 with Item 1 of 3 that may invoke OCD triggers while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - PROVOC Task 2Day 2
Subject will undergo PROVOC Task 2 with Item 2 of 3 that may invoke OCD triggers while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - PROVOC Task 3Day 2
Subject will undergo PROVOC Task 3 with Item 3 of 3 that may invoke OCD triggers while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - Non-PROVOC Task 1Day 2
Subject will undergo the same exposure task with Item 1 of 3 that does not invoke OCD triggers while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - Non-PROVOC Task 2Day 2
Subject will undergo the same exposure task with Item 2 of 3 that does not invoke OCD triggers while EEG and videotape monitors neural and facial data throughout
- Investigate for biomarkers of obsessive compulsive disorder pathophysiology through the use of behavioral tasks - Non-PROVOC Task 3Day 2
Subject will undergo the same exposure task with Item 3 of 3 that does not invoke OCD triggers while EEG and videotape monitors neural and facial data throughout