Natural History of Wilson Disease Registry

This study is creating a registry to collect information and samples from people with Wilson disease (a rare genetic disorder that causes copper to build up in organs). The goal is to better understand the disease and find the best ways to diagnose and monitor treatment. Researchers will follow people with Wilson disease over time to see how the disease progresses and how current treatments like chelation therapy and zinc treatment work. They hope to find new ways to measure treatment success. You can join if you have a known diagnosis of Wilson disease and are willing to provide informed consent. The study aims to enroll 300 participants. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information without giving any specific interventions. It aims to enroll 300 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, creating a registry, is measured at 5 years.

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NCT03334292

Natural History of Wilson Disease

Recruiting
Not specifiedAll AgesObservational
Yale University
~300 participants
Updated 2026-06-22 on ClinicalTrials.gov

At a glance

Recruiting sites
4 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Create registry for Wilson disease
Measured over 5 Years
Wilson Disease
6 sites across 6 states
Connecticut1
Florida1
Texas1
Washington1
Germany1
Surrey1

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Eligibility criteria

Inclusion

Known diagnosis of WD
Able and willing to provide informed consent for adults (Parental/guardian permission (informed consent) and if appropriate, child assent for participants \<18 (or per local Institutional Review Board (IRB) regulation)

Exclusion

Diagnosis of WD has been excluded
Unwilling to provide informed consent or assent
  • Create registry for Wilson disease5 Years

    This outcome is a binary 'yes/no' outcome as to whether or not this study can successfully create a repository with the intent to store data and specimens to support the conduct of future research on Wilson disease.