Verapamil for Neuroprotection in Stroke
This study is testing an experimental procedure using intra-arterial verapamil in people who have had an acute ischemic stroke. Verapamil is a drug that treats vasospasm (spasm of a blood vessel). Researchers want to see if giving 10 mg or 20 mg of verapamil directly into an artery after a mechanical thrombectomy (a procedure to remove a blood clot) is safe and how it affects stroke recovery. You may be able to join if you are 18 to 80 years old, have had a recent ischemic stroke, and are a candidate for mechanical thrombectomy. The study will look at bleeding complications and serious adverse events, including death, at 3 months to understand the safety of this treatment. The current recruitment status is unclear.
- Study design
- This is an interventional study with a planned enrollment of 60 participants. Participants will be randomly assigned to receive either 10 mg or 20 mg of intra-arterial verapamil.
- What's involved
- Participants will receive intra-arterial verapamil following a mechanical thrombectomy procedure.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 3 months to monitor for bleeding complications and serious adverse events.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Verapamil for Neuroprotection in Stroke
At a glance
Conditions
Where it's being run
3 sites across 2 statesWho to contact
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Inclusion
Exclusion
What this trial measures
- Number of Participants with Bleeding Complications3 months
Bleeding Complications including: symptomatic intracerebral hemorrhage (sICH), and Hemorrhagic Transformation (HT)
- Number of Participants with a Serious Adverse Event of Death3 months
Death