This study is exploring how epidural stimulation (a device implanted in your spinal cord) can help people with severe spinal cord injuries. Researchers want to see if this stimulation can improve your body's automatic functions, like blood pressure (cardiovascular stability), help you move your legs voluntarily, and assist with standing. You might be eligible if you are at least 18 years old, have had a non-progressive spinal cord injury for at least two years, cannot move your legs or stand independently, and experience issues with your blood pressure. The study aims to understand how well epidural stimulation helps with cardiovascular function and voluntary movement, with results measured for up to 20 months. The current status of this study is unclear.

Study design

This interventional study plans to enroll 36 participants with severe spinal cord injuries. Participants will be randomized into different groups receiving various types of epidural stimulation, sometimes combined with stand training.

What's involved

You would have an epidural stimulator implanted. Depending on your assigned group, you would undergo approximately 4 months of daily epidural stimulation for cardiovascular stability, or 4-7 days weekly for voluntary movement, potentially combined with stand training.

Compensation

Not stated in the trial record.

Follow-up

Your cardiovascular function and voluntary movement will be assessed for up to 20 months after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.