Panitumumab-IRDye800 for Pancreatic Cancer Surgery
This study is looking at a new way to help surgeons see pancreatic cancer more clearly during surgery. It uses a drug called panitumumab-IRDye800, which combines an antibody drug (panitumumab) with a special dye (IRDye800CW) that can be seen with a special camera. The goal is to see if this combination makes cancer cells light up, making them easier to find and remove. You might be able to join if you have pancreatic adenocarcinoma, are planning to have surgery to remove the cancer, and are generally healthy enough for surgery. The main goal is to find the best dose of panitumumab-IRDye800 to make the tumor stand out from healthy tissue. This study is currently recruiting about 27 participants.
- Study design
- This is a Phase I/II interventional study that will enroll about 27 participants. It involves a dose-escalation phase to find the optimal dose.
- What's involved
- You would receive panitumumab and then panitumumab-IRDye800 intravenously (IV). Surgery would then take place 2-5 days later, involving special imaging during the procedure.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will be followed up at 15 and 30 days after completing the study treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
At a glance
Conditions
NCT03384238
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Stanford University, School of Medicine
Palo Alto, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- George Poultsides · PRINCIPAL_INVESTIGATOR · Stanford University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Tumor to background ratio (TBR)1 day
TBR is defined as fluorescence intensity of tumor tissue compared to that of normal surrounding pancreatic tissue.