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NCT03396276

Houston Emergency Opioid Engagement System

Enrolling by Invitation
PHASE4Ages 18+InterventionalTreatment
The University of Texas Health Science Center, Houston
~3,000 participants
Updated 2025-10-01 on ClinicalTrials.gov
What's tested:SuboxoneBrief counseling in the EDReferral to outpatient treatmentFollow-up coaching

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient enrollment in outpatient treatment
Measured over at the time of enrollment in outpatient treatment
+1 more outcome measured

Conditions

Opioid Use Disorder

Explore related trials

Opioid Use Disorder

Where it's being run

1 sites across 1 states
Texas1

Study leadership

  • James R Langabeer, EMT, PhD · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center, Houston

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

In otherwise good health based on physician assessment and medical history
Tests positive in urine sample for opioids
Patients express a willingness to stop opioid use
Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence
Patients must be able to speak English
Be agreeable to and capable of signing informed consent

Exclusion

Non-English-speaking patients
Have a known sensitivity to buprenorphine or naloxone
Be physiologically dependent on alcohol, benzodiazepines or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.
Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)
Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk
Be a nursing or pregnant female

What this trial measures

  • Patient enrollment in outpatient treatmentat the time of enrollment in outpatient treatment
  • Patient retention in outpatient treatment30 days after induction in the emergency department