This study is testing if using advanced imaging, specifically Cardiac Magnetic Resonance (CMR) and Computed Tomography Angiography (CTA), can help doctors find the best place in your heart to put a special wire (lead) for a procedure called Cardiac Resynchronization Therapy (CRT). CRT is a treatment for heart failure that helps your heart beat more effectively. We want to see if guiding the CRT procedure with CMR and CTA leads to better heart function. You might be able to join if you have chronic systolic heart failure, a specific heart pumping ability (LVEF 35% or less), and meet guidelines for CRT. The main goal is to see if your heart's pumping ability (Left Ventricular End-Systolic Volume or LVESV) improves after one year. The current recruitment status is unclear.

Study design

This is an interventional study with 180 planned participants. Participants will be randomly assigned to either receive CRT guided by CMR/CTA or by a standard procedure.

What's involved

At the start, you will have CMR, CTA, echocardiography, blood tests, and exercise testing, plus complete a heart failure questionnaire. You will have follow-up visits at 6 and 12 months, and clinical follow-up for up to 3 years.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 12 months for the primary endpoint, and for up to 3 years for clinical outcomes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.