NCT03407833
Physiologic and Functional Adaptations of Insulin Sensitive Tissues
Enrolling by Invitation
Not specifiedAges 18+ObservationalVanderbilt University Medical CenterInvestigator-initiated
~500 participants
Updated 2025-12-18 on ClinicalTrials.gov
What's tested:Endoscopy biopsySurgical biopsyMixed-meal tolerance testExcised Liver Tissue Sampling
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Ability to establish organoid cultures
Measured over 12 months
Conditions
Where it's being run
1 sites across 1 statesTennessee1
Study leadership
- Charles Flynn, Ph.D. · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Eligibility criteria
Exclusion
Known history of intestinal diseases including, but not limited to, inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease) and celiac sprue.
Smoking \>7 cigarettes per day
Malabsorptive syndromes
Pregnant or breastfeeding
Recent history of malignancy (\<5 years ago)
Previous lap band surgery
Established renal disease
Previous lap band, sleeve gastrectomy, or gastric bypass surgery
Recent history of malignancy (\< 5 years ago)
Established organ dysfunction
Previous lap band, sleeve gastrectomy, or gastric bypass surgery
Alpha 1 anti-trypsin disease, Wilson's disease, viral hepatitis, alcoholic liver disease
What this trial measures
- Ability to establish organoid cultures12 months
Measure percent success rate of making organoid cultures from tissue biopsies