MERIT Study: Mammography, Early Detection, and Risk Assessment

This observational study, called MERIT, is collecting information from women who are already getting routine mammograms. Researchers will collect blood samples, mammogram images, and health information through questionnaires. The goal is to create a large collection of blood samples and a database of health and risk information. This resource can then be used for future research into breast cancer, other cancers, and women's health. You may be able to join if you are a woman between 25 and 80 years old, willing to provide blood samples and complete questionnaires, and are having a screening mammogram at a participating clinic. The study aims to follow participants for at least five years.

Study design
This is an observational study aiming to enroll 10,000 women. It does not test a specific drug or treatment.
What's involved
You would complete questionnaires and provide blood samples at the start of the study and annually for 5 years. You would also undergo standard mammography annually for 5 years.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least five years or until a breast cancer diagnosis.

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NCT03408353

Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT Study

Recruiting
Not specifiedAges 25–80Observational
M.D. Anderson Cancer Center
~10,000 participants
Updated 2026-08-11 on ClinicalTrials.gov
What's tested:Biospecimen CollectionMammographyQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Creation of a repository of blood specimens and database of imaging, clinical data, health measurements, and questionnaire data
Measured over 5 years
Breast Carcinoma
1 sites across 1 states
Texas1
  • Jessica W Leung · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Inclusion

Willingness to participate in the study and ability to provide informed consent
Willingness to complete a questionnaire and to provide a blood sample at the initial visit and at follow up annual visits
Undergoing a screening mammogram at participating sites. Subjects undergoing routine annual diagnostic mammograms or CEM as part of a screening study are also eligible.

Exclusion

Current or recent (within the prior 6 months) history of breast feeding
Personal history of breast cancer (ductal breast carcinoma in situ \[DCIS\] or invasive breast cancer)
Personal history of any other cancer (excluding in-situ, stage 0, and non-melanoma skin cancers and other pre-cancerous conditions) treated within the last 5 years.
  • Creation of a repository of blood specimens and database of imaging, clinical data, health measurements, and questionnaire data5 years