Accelerated iTBS for Postpartum Depression

This study is testing a new way to deliver intermittent theta burst stimulation (iTBS) for women with postpartum depression. iTBS is a type of transcranial magnetic stimulation (TMS) that uses magnetic pulses to stimulate specific areas of the brain. The study is looking at whether a shorter, more intense treatment schedule (either 10 times a day for 6 days or 12 times a day for 5 days) is practical and well-tolerated. You may be able to join if you are a woman between 18 and 50 years old and have been diagnosed with postpartum depression within the last year. The study will be considered successful if most participants complete the treatment and can receive the full intended dose. The current status of this study is unclear.

Study design
This is an open-label study, meaning both you and the study team will know what treatment you are receiving. It aims to enroll 40 participants.
What's involved
You would receive iTBS treatment either 10 times a day for 6 days or 12 times a day for 5 days. You would also complete assessment instruments.
Compensation
Not stated in the trial record.
Follow-up
The primary goals of the study are measured at 7 days after treatment.

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NCT03417960

Accelerated iTBS for Post Partum Depression

Recruiting
NAAges 18–50InterventionalTreatment
Medical University of South Carolina
~40 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:iTBS

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Determine feasibility and tolerability of accelerated iTBS for postpartum depression. The investigators hope to retain >80% of recruited patients (feasibility) and reach a full treatment dose of 120%rMT in >80% of enrolled women (tolerability).
Measured over 7 days
Post Partum Depression
1 sites across 1 states
South Carolina1

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  • Determine feasibility and tolerability of accelerated iTBS for postpartum depression. The investigators hope to retain >80% of recruited patients (feasibility) and reach a full treatment dose of 120%rMT in >80% of enrolled women (tolerability).7 days

    Determine feasibility and tolerability of accelerated iTBS for postpartum depression. The investigators hope to retain \>80% of recruited patients (feasibility) and reach a full treatment dose of 120%rMT in \>80% of enrolled women (tolerability).